![plex treatment plex treatment](https://rollingout.com/wp-content/uploads/2019/08/REV_CON_PLEX3StepTreatment_Group_F_V2-949x960.jpg)
?The rest of the blood is replaced back into the circulation usually with 5% albumin or a cystralloid/colloid solution. In the States, the approved PLEX machines use centrifugation. Therapeutic Plasma Exchange (PLEX/TPE): A large volume of whole blood is taken from the vein and filtered or centrifuged into various parts. ?IVIG was never tested against placebo for GBS. ?Exactly how this happens is complicated and somewhat still hypothesis, but there’s a nice explanation here ( PMID: 25561275) It is hypothesized that by binding to these sites IVIG prevents the binding of the pathologic autoantibodies. Activation of these receptors trigger immune response. ?What about the Fc portion though? This portion binds to cellular receptors (RcyF and RcRn). Thus, this portion halts potent pro-inflammation pathways. ? The Fab portion is responsible for neutralization of cytokines, complement and autoantibodies. IgG molecules have the “Fc” portion and the “V-shaped” Fab portion: Intravenous Immunoglobulin: This is a preparation of polyclonal serum IgG pooled from thousands of blood donors. Complications and Considerations for IVIG and PLEX.What if Patients aren't Getting Better?.IVIG and PLEX in Guillain-Barre Syndrome.More people would want IVIG! ? Obviously, this led me down a rabbit hole of examining my own biases and going back to the data – a post about what this deep dive revealed: So, imagine my surprise with these results:
![plex treatment plex treatment](https://afrohairpro.com/wp-content/uploads/2021/01/plex-1.png)
Also, I agree red is second best, but then orange? Really? No.
![plex treatment plex treatment](https://i1.perfumesclub.com/grande/122674.jpg)
(That this box plot exists in the world is incredible, source. They are all just flavored corn-syrup, but … we all know – the pink one is best. (Yes, I know all the meta-analyses show they have the same efficacy, but…) I thought everyone would agree PLEX is the way to go. I think of this like Starbusts. I really assumed we were all on the same page here.